Levinger L, O Jacobs*, M James*. 2001. In vitro 3' end endonucleolytic processing defect in a human mitochondrial tRNASer(UCN) precursor with the U7445C substitution, which causes non-syndromic deafness. Nucleic Acids Res. 29:4334-4340.
In this paper (published in Nucleic Acids Research), we demonstrated that the defect in a mutant mitochondrially encoded pre-tRNA associated with non-syndromic deafness is in the 3' end processing by tRNase Z. Student co-authors (Obasanjo Jacobs and Melissa James) continued in their professional education (DO School and PhD in Cell and Molecular Biology) after receiving research laboratory training with Dr. Levinger